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Taking WELLBUTRIN XL
Getting Started with WELLBUTRIN XL
Continuing Treatment with WELLBUTRIN XL
Dosing Information
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WELLBUTRIN XL vs SR
Side Effect Overview
Take the Correct Tablets

Always check that you receive WELLBUTRIN XL


The active ingredient in WELLBUTRIN XL is called bupropion. Bupropion is also in other medicines such as ZYBAN® (bupropion HCl) Sustained-Release Tablets, WELLBUTRIN SR® (bupropion HCl) Sustained-Release Tablets, and WELLBUTRIN® (bupropion HCl). If you are taking WELLBUTRIN XL, you should not take any other medicine that contains bupropion.

WELLBUTRIN XL is formulated for once-daily dosing. In some cases, patients prescribed WELLBUTRIN XL have been mistakenly given the wrong bupropion pills. Taking the wrong medicine may result in serious health problems.

Look for the name WELLBUTRIN XL printed on your tablet, and always make sure you are taking the right medicine. If your doctor prescribed WELLBUTRIN XL and your tablets do not look like the tablets below, talk to your pharmacist or doctor.

150 mg 300 mg
Tablets shown are larger than actual size.




WELLBUTRIN XL is not for everyone. There is a risk of seizure with WELLBUTRIN XL which increases with higher doses. Taking more than 450 mg/day increases the chance of serious side effects. Don't use it if you've had a seizure or eating disorder, or if you abruptly stop using alcohol or sedatives. Don't take with MAOIs, or medicines that contain bupropion. When used with a nicotine patch or alone, there is a risk of increased blood pressure, sometimes severe. To reduce risk of serious side effects, tell your doctor if you have liver or kidney problems. Other side effects may include weight loss, dry mouth, nausea, difficulty sleeping, dizziness, sore throat, constipation, or flatulence.

WELLBUTRIN XL is approved only for adults 18 years and over. In some children, teens, and young adults, antidepressants increase suicidal thoughts or actions. Whether or not you are taking antidepressants, you or your family should call the doctor right away if you have worsening depression, thoughts of suicide, or sudden or severe changes in mood or behavior, especially at the beginning of treatment or after a change in dose (see Medication Guide: Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughts or Actions).

Antidepressant Medication Guide and Patient Information for WELLBUTRIN XL
Antidepressant Medication Guide and Patient Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets), is provided in Adobe's Portable Document Format (PDF). To view these documents you will need Adobe Acrobat Reader; if you do not have it, follow the link to download a copy.
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets).
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets), is provided in Adobe's Portable Document Format (PDF). To view these documents you will need Adobe Acrobat Reader; if you do not have it, follow the link to download a copy.
If you are unable to or do not wish to download Acrobat Reader, but still wish to receive complete Prescribing Information, please click here.

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