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How WELLBUTRIN XL Works

Research suggests that depression may be caused by an imbalance of brain chemicals called neurotransmitters. Scientists believe that WELLBUTRIN XL helps balance the levels of two of these neurotransmitters called dopamine and norepinephrine.

When you have depression, nothing is more important than getting effective treatment. Clinical studies prove that WELLBUTRIN XL effectively treats depression so you can feel like yourself again. In addition, continued use (if recommended by your doctor) can lower your chances of becoming depressed in the future. Doctors have prescribed WELLBUTRIN XL to help millions of patients with depression. Although no single antidepressant works for everyone, the active ingredient in WELLBUTRIN XL (bupropion HCl) is prescribed more by psychiatrists than any other antidepressant. If you want effective treatment for depression, ask your doctor if WELLBUTRIN XL is right for you.




WELLBUTRIN XL is not for everyone. There is a risk of seizure with WELLBUTRIN XL which increases with higher doses. Taking more than 450 mg/day increases the chance of serious side effects. Don't use it if you've had a seizure or eating disorder, or if you abruptly stop using alcohol or sedatives. Don't take with MAOIs, or medicines that contain bupropion. When used with a nicotine patch or alone, there is a risk of increased blood pressure, sometimes severe. To reduce risk of serious side effects, tell your doctor if you have liver or kidney problems. Other side effects may include weight loss, dry mouth, nausea, difficulty sleeping, dizziness, sore throat, constipation, or flatulence.

WELLBUTRIN XL is approved only for adults 18 years and over. In some children, teens, and young adults, antidepressants increase suicidal thoughts or actions. Whether or not you are taking antidepressants, you or your family should call the doctor right away if you have worsening depression, thoughts of suicide, or sudden or severe changes in mood or behavior, especially at the beginning of treatment or after a change in dose (see Medication Guide: Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughts or Actions).

Antidepressant Medication Guide and Patient Information for WELLBUTRIN XL
Antidepressant Medication Guide and Patient Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets), is provided in Adobe's Portable Document Format (PDF). To view these documents you will need Adobe Acrobat Reader; if you do not have it, follow the link to download a copy.
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets).
Complete Prescribing Information for WELLBUTRIN XL® (bupropion HCl extended-release tablets), is provided in Adobe's Portable Document Format (PDF). To view these documents you will need Adobe Acrobat Reader; if you do not have it, follow the link to download a copy.
If you are unable to or do not wish to download Acrobat Reader, but still wish to receive complete Prescribing Information, please click here.

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